Article
The effect of XPD polymorphisms on digestive tract cancers risk: a meta-analysis.
PloS one - 1 Jan 2014
Du Haina, Guo Nannan, Shi Bin, Zhang Qian, Chen Zhipeng, Lu Kai, Shu Yongqian, Chen Tao, Zhu Lingjun
Abstract excerpt
BACKGROUND: The Xeroderma pigmento-sum group D gene (XPD) plays a key role in nucleotide excision repair. Single nucleotide polymorphisms (SNP) located in its functional region may alter DNA repair capacity phenotype and cancer risk. Many studies have demonstrated that XPD polymorphisms are significantly associated with digestive tract cancers risk, but the results are inconsistent. We conducted a comprehensive...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
