Article
Evaluation of insulin resistance linkage to rat chromosome 4 in SHR of a Japanese colony.
Biochemical and biophysical research communications - 15 Apr 2005
Watanabe Takehiro, Iizuka Yoko, Liang Yi-Qiang, Inomata Hyoe, Gotoda Takanari, Yanai Kazuyuki, Isobe Mitsuaki, Kato Norihiro
Abstract excerpt
The spontaneously hypertensive rat (SHR) is a model of human insulin resistance syndrome. Quantitative trait loci for cellular defects in glucose and fatty acid metabolism have been mapped to an overlapping region of rat chromosome (RNO) RNO4 in SHR of the National Institute of Health colony, where a deletion in the Cd36 gene has been implicated as the causative mutation of insulin resistance. The present study...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
