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Article

Genetic analysis of cardiovascular risk factor clustering in spontaneous hypertension.

Folia biologica - 1 Jan 2000

Pravenec M, Zídek V, Landa V, Kostka V, Musilová A, Kazdová L, Fucíková A, Krenová D, Bíla V, Kren V

Abstract excerpt

The SHR is the most widely studied animal model of hypertension. In this strain, as in many humans with essential hypertension, increased blood pressure has been reported to cluster with other risk factors for cardiovascular disease, including insulin resistance and dyslipidemia. However, the genetic mechanisms that mediate this clustering of risk factors for cardiovascular disease or the hypertension "metabolic...

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PMID: 11140856

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