Article
Quantitative trait loci on chromosomes 1 and 4 affect lipid phenotypes in the rat.
Archives of biochemistry and biophysics - 1 Jun 1998
Kovács P, Klöting I
Abstract excerpt
The spontaneously hypertensive rat (SHR/Mol) and the spontaneously diabetic BB/OK rat were crossed, and the F1 hybrids were backcrossed onto the BB/OK rat in order to search for quantitative trait loci (QTL) affecting serum total cholesterol and triglycerides on chromosomes 1, 3, 4, 10, 13, 18, and X. On chromosome 4 a QTL for triglyceride levels (lod score 3.3) was found within the region flanked by the D4Mit9...
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