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Article

Association between a variation in the phosphodiesterase 4D gene and bone mineral density.

BMC medical genetics - 7 Mar 2005

Reneland Richard H, Mah Steven, Kammerer Stefan, Hoyal Carolyn R, Marnellos George, Wilson Scott G, Sambrook Philip N, Spector Tim D, Nelson Matthew R, Braun Andreas

Abstract excerpt

BACKGROUND: Fragility fractures caused by osteoporosis are a major cause of morbidity and mortality in aging populations. Bone mineral density (BMD) is a useful surrogate marker for risk of fracture and is a highly heritable trait. The genetic variants underlying this genetic contribution are largely unknown. METHODS: We performed a large-scale association study investigating more than 25,000 single nucleotide...

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Source

Open in PubMed Open full text

Identifiers

PMID: 15752431
DOI: 10.1186/1471-2350-6-9
PMCID: PMC554993

Genes

BMP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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