Article
A new in vivo termination function for DNA polymerase I of Escherichia coli K12.
Molecular microbiology - 1 Mar 2005
Markovitz Alvin
Abstract excerpt
Escherichia coli deleted for the tus gene are viable. Thus there must be at least one other mechanism for terminating chromosome synthesis. The tus deletion strain yielded a small fraction of cells that overproduce DNA, as determined by flow cytometry after run-out chromosome replication in the presence of rifampicin and cephalexin. A plasmid, paraBAD tus+, prevented the excess DNA replication only when arabinose...
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