Article
Constraints in chromosomal inversions in Escherichia coli are not explained by replication pausing at inverted terminator-like sequences.
Molecular microbiology - 1 Apr 1990
François V, Louarn J, Patte J, Rebollo J E, Louarn J M
Abstract excerpt
Regions close to the replication terminus of the Escherichia coli chromosome are strongly refractory to genomic inversions. Since these regions also harbour polar replication terminator-like sequences or pause sites, we have investigated the possibility that slowing of replication as a result of pausing at inverted pause sites is responsible for inability to isolate stable inversions affecting these regions. A...
Topics
- Chromosome Inversion
- Chromosomes
- DNA Replication
- DNA, Bacterial
- Escherichia coli
- Genes, Regulator
- Genotype
- Mutation
- Terminator Regions, Genetic
- Trans-Activators
