Article
Differential Tus-Ter binding and lock formation: implications for DNA replication termination in Escherichia coli.
Molecular bioSystems - 1 Oct 2012
Moreau Morgane J J, Schaeffer Patrick M
Abstract excerpt
In E. coli, DNA replication termination occurs at Ter sites and is mediated by Tus. Two clusters of five Ter sites are located on each side of the terminus region and constrain replication forks in a polar manner. The polarity is due to the formation of the Tus-Ter-lock intermediate. Recently, it has been shown that DnaB helicase which unwinds DNA at the replication fork is preferentially stopped at the...
Topics
- Base Sequence
- DNA Replication
- DNA, Bacterial
- DNA-Binding Proteins
- DnaB Helicases
- Escherichia coli
- Escherichia coli Proteins
- Molecular Sequence Data
- Mutation
- Protein Binding
- Recombinant Proteins
- Surface Plasmon Resonance