Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mitochondrial functioning of constitutive iron uptake mutations in Cryptococcus neoformans.

Mycopathologia - 1 Jan 2005

Jacobson Eric S, Troy Amanda J, Nyhus Karin J

Abstract excerpt

Randomly obtained, constitutive plasma membrane ferric reductase/ferrous uptake mutants of Cryptococcus neoformans were mapped to four distinct loci by meiotic analysis. One of those loci, FRR1 , was previously found homologous to MRS3 and MRS4 of Saccharomyces cerevisiae , which determine proteins involved in mitochondrial transport of iron. We were able to complement, clone, sequence and thereby identify two of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cation Transport Proteins
Share to Cloning, Molecular
Share to Cryptococcus neoformans

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA, Fungal

Share to FMN Reductase

Share to Mitochondria

Share to Sequence Alignment

Source

Identifiers

PMID: 15750726
DOI: 10.1007/s11046-004-2223-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 9 closest

Mitochondrial functioning of constitutive iron uptake mutations in Cryptococcus neoformans.PMID 15750726Read ↗

Genetic and physiologic characterization of ferric/cupric reductase constitutive mutants of Cryptococcus neoformans.Semantic proximity Read ↗

A human fungal pathogen Cryptococcus neoformans expresses three distinct iron permease homologs.Semantic proximity Read ↗

Frataxin and mitochondrial carrier proteins, Mrs3p and Mrs4p, cooperate in providing iron for heme synthesis.Semantic proximity Read ↗

Mrs4 loss of function in fungi during adaptation to the cystic fibrosis lungSemantic proximity Read ↗

Genetic evidence that ferric reductase is required for iron uptake in Saccharomyces cerevisiae.Semantic proximity Read ↗

Identification of FRA1 and FRA2 as genes involved in regulating the yeast iron regulon in response to decreased mitochondrial iron-sulfur cluster synthesis.Semantic proximity Read ↗

Mrs3p, Mrs4p, and frataxin provide iron for Fe-S cluster synthesis in mitochondria.Semantic proximity Read ↗

The fission yeast ferric reductase gene frp1+ is required for ferric iron uptake and encodes a protein that is homologous to the gp91-phox subunit of the human NADPH phagocyte oxidoreductase.Semantic proximity Read ↗

Iron toxicity protection by truncated Ras2 GTPase in yeast strain lacking frataxin.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.