Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Structure of ginseng major latex-like protein 151 and its proposed lysophosphatidic acid-binding mechanism.

Acta crystallographica. Section D, Biological crystallography - 1 May 2015

Choi Sun Hye, Hong Myoung Ki, Kim Hyeon Joong, Ryoo Nayeon, Rhim Hyewhon, Nah Seung Yeol, Kang Lin Woo

Abstract excerpt

Lysophosphatidic acid (LPA) is a phospholipid growth factor with myriad effects on biological systems. LPA is usually present bound to animal plasma proteins such as albumin or gelsolin. When LPA complexes with plasma proteins, it binds to its cognate receptors with higher affinity than when it is free. Recently, gintonin from ginseng was found to bind to LPA and to activate mammalian LPA receptors. Gintonin...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calcium
Share to Electrophysiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Embryo, Mammalian

Share to Hippocampus

Share to Lysophospholipids

Share to Mutagenesis, Site-Directed

Share to Oocytes

Share to Xenopus laevis

Source

Identifiers

PMID: 25945569
DOI: 10.1107/S139900471500259X

Genes

LPA

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Structure of ginseng major latex-like protein 151 and its proposed lysophosphatidic acid-binding mechanism.PMID 25945569Read ↗

Gintonin, newly identified compounds from ginseng, is novel lysophosphatidic acids-protein complexes and activates G protein-coupled lysophosphatidic acid receptors with high affinity.Semantic proximity Read ↗

In silico approach for the prospecting of molecules from Cereus jamacaru (Cereeae) in the treatment of obesity and cardiovascular diseasesSemantic proximity Read ↗

Cyclic phosphatidic acid is produced by GDE7 in the ER lumen as a lysophospholipid mediatorSemantic proximity Read ↗

Structural determinants for phosphatidic acid regulation of phospholipase C-beta1.Semantic proximity Read ↗

A conserved and druggable pocket in class B G protein coupled receptors for orally active small molecule agonistsSemantic proximity Read ↗

PGRMC1 acts as a size-selective cargo receptor to drive ER-phagic clearance of mutant prohormones.Semantic proximity Read ↗

N-Glycosylation of Asparagine 130 in the Extracellular Domain of the Human Calcitonin Receptor Significantly Increases Peptide Hormone Affinity.Semantic proximity Read ↗

Target molecules of food phytochemicals: Food science bound for the next dimensionSemantic proximity Read ↗

A conserved asparagine residue in the inner surface of BRI1 superhelix is essential for protein native conformation.Semantic proximity Read ↗

CaaX-motif-adjacent residues influence G protein gamma (Gγ) prenylation under suboptimal conditions.Semantic proximity Read ↗

Development of chemical tools to study protein palmitoylation and palmitoyl acyltransferasesSemantic proximity Read ↗

Structural basis for the activation of PLC-γ isozymes by phosphorylation and cancer-associated mutations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.