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Article

Profilin-mediated competition between capping protein and formin Cdc12p during cytokinesis in fission yeast.

Molecular biology of the cell - 1 May 2005

Kovar David R, Wu Jian-Qiu, Pollard Thomas D

Abstract excerpt

Fission yeast capping protein SpCP is a heterodimer of two subunits (Acp1p and Acp2p) that binds actin filament barbed ends. Neither acp1 nor acp2 is required for viability, but cells lacking either or both subunits have cytokinesis defects under stressful conditions, including elevated temperature, osmotic stress, or in combination with numerous mild mutations in genes important for cytokinesis. Defects arise as...

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Identifiers

PMID: 15743909
DOI: 10.1091/mbc.e04-09-0781
PMCID: PMC1087237

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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