Article

Fission yeast TRP channel Pkd2p localizes to the cleavage furrow and regulates cell separation during cytokinesis

2018-05-07

Abstract excerpt

Force plays a central role in separating daughter cells during cytokinesis, the last stage of cell division. However, the mechanism of force-sensing during cytokinesis remains unknown. Here we discovered that Pkd2p, a putative force-sensing TRP channel, localizes to the cleavage furrow during cytokinesis of the fission yeast, Schizosaccharomyces pombe . Pkd2p, whose human homologues are associated with Autosomal...

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Literature Corpus work: 0b9e29d6-71ae-5328-b0ed-f56c8cdac007
DOI: 10.1101/316380

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