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Article

Fission yeast TRP channel Pkd2p localizes to the cleavage furrow and regulates cell separation during cytokinesis.

Molecular biology of the cell - 15 Jul 2019

Morris Zachary, Sinha Debatrayee, Poddar Abhishek, Morris Brittni, Chen Qian

Abstract excerpt

Force plays a central role in separating daughter cells during cytokinesis, the last stage of cell division. However, the mechanism of force sensing during cytokinesis remains unknown. Here we discovered that Pkd2p, a putative force-sensing transient receptor potential channel, localizes to the cleavage furrow during cytokinesis of the fission yeast, Schizosaccharomyces pombe. Pkd2p, whose human homologues are...

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Identifiers

PMID: 31116668
DOI: 10.1091/mbc.E18-04-0270
PMCID: PMC6727746

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Fission yeast TRP channel Pkd2p localizes to the cleavage furrow and regulates cell separation during cytokinesis.PMID 31116668Read ↗

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