Article
Regulation and targeting of the fission yeast formin cdc12p in cytokinesis.
Molecular biology of the cell - 1 May 2008
Yonetani Ann, Lustig Raymond J, Moseley James B, Takeda Tetsuya, Goode Bruce L, Chang Fred
Abstract excerpt
Formins are conserved actin nucleators which promote the assembly of actin filaments for the formation of diverse actin structures. In fission yeast Schizosaccharomyces pombe, the formin cdc12p is required specifically in assembly of the actin-based contractile ring during cytokinesis. Here, using a mutational analysis of cdc12p, we identify regions of cdc12p responsible for ring assembly and localization....
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