Article
Tapasin gene polymorphism in systemic onset juvenile rheumatoid arthritis: a family-based case-control study.
Arthritis research & therapy - 1 Jan 2005
Bukulmez Hulya, Fife Mark, Tsoras Monica, Thompson Susan D, Twine Natalie A, Woo Patricia, Olson Jane M, Elston Robert C, Glass David N, Colbert Robert A
Abstract excerpt
Juvenile rheumatoid arthritis (JRA) comprises a group of chronic systemic inflammatory disorders that primarily affect joints and can cause long-term disability. JRA is likely to be a complex genetic trait, or a series of such traits, with both genetic and environmental factors contributing to the risk for developing the disease and to its progression. The HLA region on the short arm of chromosome 6 has been...
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