Article
Juvenile idiopathic arthritis subtype- and sex-specific associations with genetic variants in the PSMA6/PSMC6/PSMA3 gene cluster.
Pediatrics and neonatology - 1 Oct 2014
Sjakste Tatjana, Paramonova Natalia, Rumba-Rozenfelde Ingrida, Trapina Ilva, Sugoka Olga, Sjakste Nikolajs
Abstract excerpt
BACKGROUND: The ubiquitin proteasome system plays an exceptional biological role in the antigen processing and immune response and it could potentially be involved in pathogenesis of many immunity-related diseases, including juvenile idiopathic arthritis (JIA). METHODS: The PSMB5 (rs11543947), PSMA6 (rs2277460, rs1048990), PSMC6 (rs2295826, rs2295827), and PSMA3 () proteasomal genes were genotyped on JIA...
