Article
Genetic background of juvenile idiopathic arthritis.
Autoimmunity - 1 Sept 2014
Chistiakov Dimitry A, Savost'anov Kirill V, Baranov Alexander A
Abstract excerpt
Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatologic disease in children. JIA is a group of disorders that share the clinical manifestation of chronic joint inflammation. The human leukocyte antigen region (HLA) seems to be a major susceptibility locus for JIA that is estimated to account for 17% of familial segregation of the disease. To date, around 20 non-HLA loci conferring...
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