Article
The susceptibility loci juvenile idiopathic arthritis shares with other autoimmune diseases extend to PTPN2, COG6, and ANGPT1.
Arthritis and rheumatism - 1 Nov 2010
Thompson Susan D, Sudman Marc, Ramos Paula S, Marion Miranda C, Ryan Mary, Tsoras Monica, Weiler Tracey, Wagner Michael, Keddache Mehdi, Haas J Peter, Mueller Cornelia, Prahalad Sampath, Bohnsack John, Wise Carol A, Punaro Marilynn, Zhang Dongping, Rosé Carlos D, Comeau Mary E, Divers Jasmin, Glass David N, Langefeld Carl D
Abstract excerpt
OBJECTIVE: To test for associations between non-major histocompatibility complex susceptibility loci previously reported in autoimmune diseases and juvenile idiopathic arthritis (JIA). METHODS: Published autoimmune disease genome-wide association studies were reviewed, and 519 single-nucleotide polymorphisms (SNPs) were selected for association testing. The initial cohort included 809 JIA cases and 3,535 controls...
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