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Article

Immunogenetics of juvenile idiopathic arthritis: A comprehensive review.

Journal of autoimmunity - 1 Nov 2015

Hersh Aimee O, Prahalad Sampath

Abstract excerpt

Juvenile idiopathic arthritis (JIA) is the most common chronic inflammatory arthropathy of childhood. Juvenile idiopathic arthritis is believed to be a complex genetic trait influenced by both genetic and environmental factors. Twin and family studies suggest a substantial role for genetic factors in the predisposition to JIA. Describing the genetics is complicated by the heterogeneity of JIA; the International...

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Source

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Identifiers

PMID: 26305060
DOI: 10.1016/j.jaut.2015.08.002
PMCID: PMC4838197

Genes

PTPN22
STAT4
PTPN2
TNFAIP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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