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Article

Osteopontin gene polymorphisms in Spanish patients with rheumatoid arthritis.

The Journal of rheumatology - 1 Mar 2005

Urcelay Elena, Martínez Alfonso, Mas-Fontao Ana, Peris-Pertusa Alejandra, Pascual-Salcedo Dora, Balsa Alejandro, Fernández-Arquero Miguel, de la Concha Emilio

Abstract excerpt

OBJECTIVE: Rheumatoid arthritis (RA) is an autoimmune disease of unknown etiology characterized by cartilage and bone destruction. The main genetic determinant to RA, the shared epitope, maps to the HLA-DR locus, although this is not the only risk factor. The osteopontin (OPN) gene, with pleiotropic functions in inflammatory and immune responses, has been implicated in the pathogenesis of RA. We studied the...

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Share to Arthritis, Rheumatoid
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Epitopes

Share to Haplotypes

Share to HLA-DR Antigens

Share to Osteopontin

Share to Sialoglycoproteins

Source

Identifiers

PMID: 15742429

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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