Article
PADI4 polymorphisms are not associated with rheumatoid arthritis in the Spanish population.
Rheumatology (Oxford, England) - 1 Oct 2005
Martinez A, Valdivia A, Pascual-Salcedo D, Lamas J Ramón, Fernández-Arquero M, Balsa A, Fernández-Gutiérrez B, de la Concha E G, Urcelay E
Abstract excerpt
OBJECTIVES: The presence of anti-citrullinated peptide antibodies is the most specific serological marker known of rheumatoid arthritis (RA). The PADI4 gene, encoding a haematopoietic isoform of the peptidylarginine deiminase citrullinating enzyme, has recently been associated with susceptibility to RA in the Japanese population. A subsequent UK report could not confirm this association, and a later French study...
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