Article
Noninherited maternal antigens do not play a role in rheumatoid arthritis susceptibility in Europe. European Consortium on Rheumatoid Arthritis Families.
Arthritis and rheumatism - 1 Apr 2000
Barrera P, Balsa A, Alves H, Westhovens R, Maenaut K, Cornélis F, Fritz P, Bardin T, de Almeida G, Lopes-Vaz A, Pascual Salcedo D, de la Concha E G, Radstake T R, van de Putte L B, Migliorini P, Prud'homme J F, Charron D, Spyropoulou M, Mendes A, Spaepen M, Martinez M, Lepage V, Stravopoulos C
Abstract excerpt
OBJECTIVE: It has been proposed that noninherited maternal antigens (NIMA) (HLA-DR antigens) might play a role in susceptibility to rheumatoid arthritis (RA), especially in patients who are not genetically predisposed, such as those who are HLA-DR4 and/or shared epitope (SE) negative. The present study was undertaken to test the NIMA hypothesis in a large cohort of European RA patients assembled by the European...
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