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Article

Genomic control for association studies under various genetic models.

Biometrics - 1 Mar 2005

Zheng Gang, Freidlin Boris, Li Zhaohai, Gastwirth Joseph L

Abstract excerpt

Case-control studies are commonly used to study whether a candidate allele and a disease are associated. However, spurious association can arise due to population substructure or cryptic relatedness, which cause the variance of the trend test to increase. Devlin and Roeder derived the appropriate variance inflation factor (VIF) for the trend test and proposed a novel genomic control (GC) approach to estimate VIF...

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Source

Identifiers

PMID: 15737092
DOI: 10.1111/j.0006-341X.2005.t01-1-.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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