Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The power of genomic control.

American journal of human genetics - 1 Jun 2000

Bacanu S A, Devlin B, Roeder K

Abstract excerpt

Although association analysis is a useful tool for uncovering the genetic underpinnings of complex traits, its utility is diminished by population substructure, which can produce spurious association between phenotype and genotype within population-based samples. Because family-based designs are robust against substructure, they have risen to the fore of association analysis. Yet, if population substructure could...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Computer Simulation
Share to Europe
Share to Genetics, Population

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genome, Human

Share to Linkage Disequilibrium

Share to Nuclear Family

Share to Probability

Share to Regression Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 10801388
DOI: 10.1086/302929
PMCID: PMC1378064

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The power of genomic control.PMID 10801388Read ↗

The power of the transmission disequilibrium test (TDT) with both case-parent and control-parent trios.Semantic proximity Read ↗

Association studies for quantitative traits in structured populations.Semantic proximity Read ↗

Utilizing population controls in rare-variant case-parent association tests.Semantic proximity Read ↗

Robust genomic control for association studies.Semantic proximity Read ↗

Case-control studies in the genomic era: a clinician's guide.Semantic proximity Read ↗

Genomic control, a new approach to genetic-based association studies.Semantic proximity Read ↗

Case-control analyses: Geneopardy!Semantic proximity Read ↗

Disease and Polygenic Architecture: Avoid Trio Design and Appropriately Account for Unscreened Control Subjects for Common Disease.Semantic proximity Read ↗

False discovery rate control in genome-wide association studies with population structure.Semantic proximity Read ↗

Design efficiency in genetic association studies.Semantic proximity Read ↗

A hybrid design: case-parent triads supplemented by control-mother dyads.Semantic proximity Read ↗

Optimizing the power of genome-wide association studies by using publicly available reference samples to expand the control group.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.