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Article

Correcting for cryptic relatedness by a regression-based genomic control method.

BMC genetics - 2 Dec 2009

Yan Ting, Hou Bo, Yang Yaning

Abstract excerpt

BACKGROUND: Genomic control (GC) method is a useful tool to correct for the cryptic relatedness in population-based association studies. It was originally proposed for correcting for the variance inflation of Cochran-Armitage's additive trend test by using information from unlinked null markers, and was later generalized to be applicable to other tests with the additional requirement that the null markers are...

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PMID: 19954543
DOI: 10.1186/1471-2156-10-78
PMCID: PMC3087514

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