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Article

Bayes factor based on the trend test incorporating Hardy-Weinberg disequilibrium: more power to detect genetic association.

Annals of human genetics - 1 Jul 2012

Xu Jinfeng, Yuan Ao, Zheng Gang

Abstract excerpt

In the analysis of case-control genetic association, the trend test and Pearson's test are the two most commonly used tests. In genome-wide association studies (GWAS), Bayes factor (BF) is a useful tool to support significant P-values, and a better measure than P-value when results are compared across studies with different sample sizes. When reporting the P-value of the trend test, we propose a BF directly based...

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Identifiers

PMID: 22607017
DOI: 10.1111/j.1469-1809.2012.00714.x
PMCID: PMC3372619

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