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Article

The tumor suppressor RASSF1A in human carcinogenesis: an update.

1 Apr 2005

Abstract excerpt

Loss of heterozygosity of the small arm of chromosome 3 is one of the most common alterations in human cancer. Most notably, a segment in 3p21.3 is frequently lost in lung cancer and several other carcinomas. We and others have identified a novel Ras effector at this segment, which was termed Ras Association Domain family 1 (RASSF1A) gene. RASSF1 consists of two main variants (RASSF1A and RASSF1C), which are...

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Identifiers

PMID: 15736067
DOI: 10.14670/hh-20.645

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