Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Frequent hypermethylation of promoter region of <i>RASSF1A</i> in tumor tissues and voided urine of urinary bladder cancer patients

14 Feb 2003

Abstract excerpt

High frequency loss of 3p21.3 region where RASSF1A located was demonstrated in several tumors. We aimed to investigate the methylation status of RASSF1A and the frequency of LOH in 3p21.3 region in bladder cancer. Three bladder cancer cell lines, 40 cases of bladder TCC and 14 cases of paired voided urine samples were subjected to methylation analysis. By methylation specific PCR, complete methylation of promoter...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bladder and Urothelial Cancer Treatments
Share to Cancer-related gene regulation
Share to Epigenetics and DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12594816
DOI: 10.1002/ijc.10971

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Frequent hypermethylation of promoter region of <i>RASSF1A</i> in tumor tissues and voided urine of urinary bladder cancer patientsPMID 12594816Read ↗

The association of RAS association domain family Protein1A (RASSF1A) methylation states and bladder cancer risk: a systematic review and meta-analysis.Semantic proximity Read ↗

Aberrant Methylation of RASSF1A gene Contribute to the Risk of Renal Cell Carcinoma: a Meta-Analysis.Semantic proximity Read ↗

DNA Hypermethylation of a panel of genes as an urinary biomarker for bladder cancer diagnosisSemantic proximity Read ↗

The tumor suppressor RASSF1A in human carcinogenesis: an update.Semantic proximity Read ↗

Association between RASSF1A promoter methylation and renal cell cancer susceptibility: a meta-analysis.Semantic proximity Read ↗

Distinct DNA methylation epigenotypes in bladder cancer from different Chinese sub-populations and its implication in cancer detection using voided urine.Semantic proximity Read ↗

Detection of bladder cancer in urine sediments by a hypermethylation panel of selected tumor suppressor genesSemantic proximity Read ↗

Hypermethylation of the tumor suppressor gene RASSFIA and frequent concomitant loss of heterozygosity at 3p21 in cervical cancers.Semantic proximity Read ↗

Detection of Bladder Cancer in Urine by a Tumor Suppressor Gene Hypermethylation PanelSemantic proximity Read ↗

Ras-association domain family 1 (RASSF1A) gene regulates progression, migration and invasion of bladder cancerSemantic proximity Read ↗

The association between RASSF1A promoter methylation and prostate cancer: evidence from 19 published studies.Semantic proximity Read ↗

Promoter Hypermethylation in Tumour Suppressor Genes Shows Association with Stage, Grade and Invasiveness of Bladder CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.