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Article

Genetic factors in catechol estrogen metabolism in relation to the risk of endometrial cancer.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Feb 2005

Doherty Jennifer A, Weiss Noel S, Freeman Robert J, Dightman Douglas A, Thornton Perry J, Houck John R, Voigt Lynda F, Rossing Mary Anne, Schwartz Stephen M, Chen Chu

Abstract excerpt

2-Hydroxylated metabolites of estrogen have been shown to have antiangiogenic effects and inhibit tumor cell proliferation, whereas 4-hydroxylated metabolites have been implicated in carcinogenesis. We examined whether polymorphisms in certain genes involved in estrogen metabolism are associated with endometrial cancer risk in a population-based case-control study with 371 cases and 420 controls. Based on...

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Identifiers

PMID: 15734958
DOI: 10.1158/1055-9965.EPI-04-0479

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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