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Ovarian cancer risk and polymorphisms involved in estrogen catabolism.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Mar 2007

Holt Sarah K, Rossing Mary Anne, Malone Kathleen E, Schwartz Stephen M, Weiss Noel S, Chen Chu

Abstract excerpt

Polymorphisms within genes responsible for estrogen catabolism could alter cellular levels of genotoxic 4-hydroxylated catechol estrogens and antiangiogenic 2-methoxyestradiol, thus influencing risk of developing ovarian cancer. We carried out a population-based case-control study of 310 epithelial ovarian cancer cases and 585 controls in African-American and Caucasian women ages 35 to 54 years from Seattle,...

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PMID: 17372243
DOI: 10.1158/1055-9965.EPI-06-0831

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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