Article
Radiosensitization of Ras-mutated human tumor cells in vitro by the specific EGF receptor antagonist BIBX1382BS.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology - 1 Feb 2005
Toulany Mahmoud, Dittmann Klaus, Baumann Michael, Rodemann H Peter
Abstract excerpt
BACKGROUND AND PURPOSE: To investigate the cellular and molecular consequences of antagonizing radiation-induced EGFR-activation in vitro. PATIENTS AND METHODS: The effect of the EGFR tyrosine kinase inhibitor BIBX1382BS on radiation sensitivity was determined after single- and fractionated-dose...
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