Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Enhanced radiosensitivity of NSCLC cells by transducer of erbB2.1 (TOB1) through modulation of the MAPK/ERK pathway

12 Apr 2013

Abstract excerpt

Transducer of erbB2.1 (TOB1) is a member of the B-cell translocation gene (BTG)/transducer of erbB2 (TOB) anti‑proliferative protein family. Previous studies have demonstrated that overexpression of TOB1 significantly enhances the radiosensitivity of breast and cervical cancer cells. However, the potential mechanisms of TOB1 are still debated. In the present study, we evaluated the effects of infrared (IR)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related gene regulation
Share to Glutathione Transferases and Polymorphisms
Share to Lung Cancer Treatments and Mutations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23589165
DOI: 10.3892/or.2013.2403

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Enhanced radiosensitivity of NSCLC cells by transducer of erbB2.1 (TOB1) through modulation of the MAPK/ERK pathwayPMID 23589165Read ↗

Nimotuzumab Enhances the Radiosensitivity of Cancer Cells In Vitro by Inhibiting Radiation-Induced DNA Damage RepairSemantic proximity Read ↗

Radiation-induced signaling pathways that promote cancer cell survival (Review)Semantic proximity Read ↗

Radiation-induced EGFR-signaling and control of DNA-damage repairSemantic proximity Read ↗

[Ionizing Radiation Reduces TKI Resistance Caused by T790M Mutation in NSCLC Cell Lines].Semantic proximity Read ↗

The p53–53BP1-Related Survival of A549 and H1299 Human Lung Cancer Cells after Multifractionated Radiotherapy Demonstrated Different Response to Additional Acute X-ray ExposureSemantic proximity Read ↗

Targeting Aberrant DNA Double-Strand Break Repair in Triple-Negative Breast Cancer with Alpha-Particle Emitter Radiolabeled Anti-EGFR AntibodySemantic proximity Read ↗

Effect of therapies-mediated modulation of telomere and/or telomerase on cancer cells radiosensitivitySemantic proximity Read ↗

BPIFB1 (LPLUNC1) inhibits radioresistance in nasopharyngeal carcinoma by inhibiting VTN expressionSemantic proximity Read ↗

Silencing of XRCC4 increases radiosensitivity of triple-negative breast cancer cellsSemantic proximity Read ↗

Radiation promotes malignant phenotypes through SRC in breast cancer cells.Semantic proximity Read ↗

Radiosensitization of Ras-mutated human tumor cells in vitro by the specific EGF receptor antagonist BIBX1382BS.Semantic proximity Read ↗

Fluzoparib increases radiation sensitivity of non-small cell lung cancer (NSCLC) cells without BRCA1/2 mutation, a novel PARP1 inhibitor undergoing clinical trials.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.