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Article

Interaction of radiation and gefitinib on a human lung cancer cell line with mutant EGFR gene in vitro.

Anticancer research - 1 Nov 2012

Sato Yumi, Ebara Takeshi, Sunaga Noriaki, Takahashi Takeo, Nakano Takashi

Abstract excerpt

AIM: To investigate the effect of gefitinib in combination with irradiation using HCC827 cells, a human lung cancer cell line bearing epidermal growth factor receptor (EGFR) mutation. MATERIALS AND METHODS: The effects of treatment with radiation with and without gefitinib on HCC827 cells were assessed using a clonogenic assay. Apoptosis was measured by flow cytometry and EGFR signal transduction was evaluated by...

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Source

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PMID: 23155255

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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