Article
The flexible loop of Bcl-2 is required for molecular interaction with immunosuppressant FK-506 binding protein 38 (FKBP38).
FEBS letters - 28 Feb 2005
Kang Cong Bao, Tai Jeff, Chia Joel, Yoon Ho Sup
Abstract excerpt
Bcl-2 contains an unusually long loop between the first and the second helices. This loop has been shown to be highly flexible based on NMR and X-ray crystallographic analyses of this region. Bcl-2 is regulated at the posttranslational level through phosphorylation of specific residues within the...
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