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Article

Posttranslational modifications of Bcl2 family members--a potential therapeutic target for human malignancy.

Frontiers in bioscience : a journal and virtual library - 1 May 2006

Basu Aruna, DuBois Garrett, Haldar Subrata

Abstract excerpt

Apoptosis is a process that can occur normally, such as during tissue remodeling, embryogenesis or abnormally during certain pathologies, such as cancer. The identification of the Bcl2 as well as IAP family members has suggested that excessive inhibition of apoptosis may constitute a common feature of all known human cancers-the ability to influence their onset, progression and outcome. Bcl2 family proteins are...

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Identifiers

PMID: 16368533
DOI: 10.2741/1900

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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