Article
Use of fluorescence resonance energy transfer for rapid detection of isoniazid resistance in Mycobacterium tuberculosis clinical isolates.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease - 1 Feb 2005
Saribas Z, Yurdakul P, Alp A, Gunalp A
Abstract excerpt
SETTING: Rapid detection of drug resistance in Mycobacterium tuberculosis is important to select effective treatment and prevent transmission of resistant isolates. OBJECTIVE: To evaluate the use of fluorescence resonance energy transfer (FRET) for rapid detection of isoniazid (INH) resistance in M. tuberculosis clinical isolates. DESIGN: One hundred INH-resistant and 50 INH-susceptible isolates of M....
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