Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fast test for assessing the susceptibility of Mycobacterium tuberculosis to isoniazid and rifampin by real-time PCR.

Memorias do Instituto Oswaldo Cruz - 1 Nov 2012

Gonçalves Maria Gisele, Fukasawa Lucila Okuyama, Oliveira Rosangela Siqueira, Salgado Maristela Marques, Harrison Lee H, Shutt Kathleen A, Sacchi Claudio Tavares

Abstract excerpt

Mycobacterium tuberculosis is the bacterium that causes tuberculosis (TB), a leading cause of death from infectious disease worldwide. Rapid diagnosis of resistant strains is important for the control of TB. Real-time polymerase chain reaction (RT-PCR) assays may detect all of the mutations that occur in the M. tuberculosis 81-bp core region of the rpoB gene, which is responsible for resistance to rifampin (RIF)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antitubercular Agents
Share to Catalase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA-Directed RNA Polymerases

Share to Isoniazid

Share to Mycobacterium tuberculosis

Share to Oxidoreductases

Share to Real-Time Polymerase Chain Reaction

Share to Rifampin

Source

Open in PubMed Open full text

Identifiers

PMID: 23147147
DOI: 10.1590/s0074-02762012000700011
PMCID: PMC4643165

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fast test for assessing the susceptibility of Mycobacterium tuberculosis to isoniazid and rifampin by real-time PCR.PMID 23147147Read ↗

Multi-Fluorescence Real-Time PCR Assay for Detection of RIF and INH Resistance of M. tuberculosisSemantic proximity Read ↗

New real-time PCR able to detect in a single tube multiple rifampin resistance mutations and high-level isoniazid resistance mutations in Mycobacterium tuberculosis.Semantic proximity Read ↗

Multidrug-resistant tuberculosis.Semantic proximity Read ↗

Rapid direct detection of multiple rifampin and isoniazid resistance mutations in Mycobacterium tuberculosis in respiratory samples by real-time PCR.Semantic proximity Read ↗

Use of real-time PCR and fluorimetry for rapid detection of rifampin and isoniazid resistance-associated mutations in Mycobacterium tuberculosis.Semantic proximity Read ↗

Analytical and clinical performance characteristics of the Abbott RealTime MTB RIF/INH Resistance, an assay for the detection of rifampicin and isoniazid resistant Mycobacterium tuberculosis in pulmonary specimens.Semantic proximity Read ↗

Direct detection in clinical samples of multiple gene mutations causing resistance of Mycobacterium tuberculosis to isoniazid and rifampicin using fluorogenic probes.Semantic proximity Read ↗

Rapid Detection of Multidrug-Resistant Mycobacterium tube rculosis by Use of Real-Time PCR and High-Resolution Melt AnalysisSemantic proximity Read ↗

Multidrug-resistant tuberculosis: rapid detection of resistance to rifampin and high or low levels of isoniazid in clinical specimens and isolatesSemantic proximity Read ↗

Rapid identification of mycobacteria and rapid detection of drug resistance in Mycobacterium tuberculosis in cultured isolates and in respiratory specimens.Semantic proximity Read ↗

Detection of genomic mutations in katG and rpoB genes among multidrug-resistant Mycobacterium tuberculosis isolates from Tehran, IranSemantic proximity Read ↗

Detection of rifampin resistance in Mycobacterium tuberculosis in a single tube with molecular beacons.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.