Article
Microplate hybridization assay for detection of isoniazid resistance in Mycobacterium tuberculosis.
BMB reports - 28 Feb 2009
Han Hye Eun, Lee In Soo, Hwang Joo Hwan, Bang Hye Eun, Kim Yeun, Cho Sang-Nae, Kim Tae Ue, Lee Hye Young
Abstract excerpt
Early and accurate detection of drug resistant Mycobacterium tuberculosis can improve both the treatment outcome and public health control of tuberculosis. A number of molecular-based techniques have been developed including ones using probe molecules that target drug resistance-related mutations. Although these techniques are highly specific and sensitive, mixed signals can be obtained when the drug resistant...
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