Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An ex vivo model for functional studies of myofibroblasts.

Laboratory investigation; a journal of technical methods and pathology - 1 May 2005

Kilarski Witold W, Jura Natalia, Gerwins Pär

Abstract excerpt

Migration, proliferation and invasive growth of myofibroblasts are key cellular events during formation of granulation tissue in situations of wound healing, arteriosclerosis and tumor growth. To study the invasive phenotype of myofibroblasts, we established an assay where arterial tissue from chicken embryos was embedded in fibrin gels and stimulated with growth factors. Addition of serum, PDGF-BB and FGF-2, but...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aorta
Share to Becaplermin
Share to Fibroblast Growth Factor 2

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Neovascularization, Physiologic

Share to Platelet-Derived Growth Factor

Share to Proto-Oncogene Proteins c-sis

Share to Spheroids, Cellular

Share to Wound Healing

Source

Identifiers

PMID: 15723087
DOI: 10.1038/labinvest.3700255

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An ex vivo model for functional studies of myofibroblasts.PMID 15723087Read ↗

The chicken chorioallantoic membrane assay revisited – A face-lifted approach for new perspectives in placenta researchSemantic proximity Read ↗

Establishment of fibroblast and myofibroblast phenotypes for use in in vitro co-culture models.Semantic proximity Read ↗

Fibrocytes induce an angiogenic phenotype in cultured endothelial cells and promote angiogenesis in vivo.Semantic proximity Read ↗

Progressive modulation of endothelial phenotype during in vitro blood vessel formation.Semantic proximity Read ↗

Culture of large vessel endothelial cells on floating collagen gels promotes a phenotype characteristic of endothelium in vivo.Semantic proximity Read ↗

Large-vessel endothelium switches to a microvascular phenotype during angiogenesis in collagen gel culture of rat aorta.Semantic proximity Read ↗

Mechanically altered embryonic chicken endothelial cells change their phenotype to an epithelioid phenotype.Semantic proximity Read ↗

Matrix metalloproteinase-2 is required for the switch to the angiogenic phenotype in a tumor model.Semantic proximity Read ↗

Dermal Fibroblasts from the Red Duroc Pig Have an Inherently Fibrogenic Phenotype: An In Vitro Model of Fibroproliferative Scarring.Semantic proximity Read ↗

Hypoxia generates a more invasive phenotype of tumour cells: an in vivo experimental setup based on the chorioallantoic membrane.Semantic proximity Read ↗

Differential expression of type I collagen and cellular fibronectin isoforms in endothelial cell variants.Semantic proximity Read ↗

Identification, paracrine generation, and possible function of human breast carcinoma myofibroblasts in culture.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.