Article
Identification, paracrine generation, and possible function of human breast carcinoma myofibroblasts in culture.
In vitro cellular & developmental biology : journal of the Tissue Culture Association - 1 Apr 1992
Rønnov-Jessen L, Van Deurs B, Nielsen M, Petersen O W
Abstract excerpt
Myofibroblasts from human breast carcinomas were identified and experimentally generated in culture, and a possible function was examined. The frequency of alpha-smooth muscle actin immunoreactive cells was evaluated as a measure of myofibroblast differentiation in primary culture. Few or no alph...
Topics
- Actins
- Breast Neoplasms
- Cell Differentiation
- Cell Movement
- Fibroblasts
- Fluorescent Antibody Technique
- Humans
- Immunoblotting
- Immunoenzyme Techniques
- Muscle, Smooth, Vascular
- Phenotype
- Plasminogen
- Tumor Cells, Cultured