Large-vessel endothelium switches to a microvascular phenotype during angiogenesis in collagen gel culture of rat aorta.

doi:10.1016/0021-9150(92)90022-9

Back to search

Article

Large-vessel endothelium switches to a microvascular phenotype during angiogenesis in collagen gel culture of rat aorta.

Atherosclerosis - 1 Aug 1992

Nicosia R F, Bonanno E, Villaschi S

Abstract excerpt

The purpose of this study was to investigate the vasoformative behavior in vitro of the native intimal endothelium of the rat aorta. To visualize the intimal surface directly, thoracic aortas were everted using a procedure that sequestered adventitial cells and possible remnant microvessels of pe...

Topics

Animals
Aorta
Collagen
Culture Techniques
Endothelium, Vascular
Gels
Histological Techniques
Immunohistochemistry
Male
Microcirculation
Microscopy, Electron
Neovascularization, Pathologic
Phenotype
Rats
Rats, Inbred F344

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.