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Article

Establishment of fibroblast and myofibroblast phenotypes for use in in vitro co-culture models.

Biochimie - 1 Apr 2023

Ramklowan D S H, Snyman C, van de Vyver M, Niesler C U

Abstract excerpt

Fibroblasts function to secrete and modify components of the extracellular matrix. During wound healing, fibroblasts migrate to the site of injury and differentiate into contractile myofibroblasts; this differentiation is characterised by an increased contractile capacity. Fully differentiated myofibroblasts can be distinguished from fibroblasts via the higher expression of α-smooth muscle actin as well as a...

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Identifiers

PMID: 36343754
DOI: 10.1016/j.biochi.2022.10.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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