Article
Similarity in recombination rate estimates highly correlates with genetic differentiation in humans.
PloS one - 28 Mar 2011
Laayouni Hafid, Montanucci Ludovica, Sikora Martin, Melé Marta, Dall'Olio Giovanni Marco, Lorente-Galdos Belén, McGee Kate M, Graffelman Jan, Awadalla Philip, Bosch Elena, Comas David, Navarro Arcadi, Calafell Francesc, Casals Ferran, Bertranpetit Jaume
Abstract excerpt
Recombination varies greatly among species, as illustrated by the poor conservation of the recombination landscape between humans and chimpanzees. Thus, shorter evolutionary time frames are needed to understand the evolution of recombination. Here, we analyze its recent evolution in humans. We calculated the recombination rates between adjacent pairs of 636,933 common single-nucleotide polymorphism loci in 28...
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