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Article

Comparison of fine-scale recombination rates in humans and chimpanzees.

Science (New York, N.Y.) - 1 Apr 2005

Winckler Wendy, Myers Simon R, Richter Daniel J, Onofrio Robert C, McDonald Gavin J, Bontrop Ronald E, McVean Gilean A T, Gabriel Stacey B, Reich David, Donnelly Peter, Altshuler David

Abstract excerpt

We compared fine-scale recombination rates at orthologous loci in humans and chimpanzees by analyzing polymorphism data in both species. Strong statistical evidence for hotspots of recombination was obtained in both species. Despite approximately 99% identity at the level of DNA sequence, however...

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PMID: 15705809
DOI: 10.1126/science.1105322

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-15705809-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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