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Article

Lysophosphatidylcholine induces tPA gene expression through CRE-dependent mechanism.

Biochemical and biophysical research communications - 1 Apr 2005

Sheikh Abdullah Md, Ochi Hiroshi, Masuda Junichi

Abstract excerpt

Lysophosphatidylcholine (lysoPC) is implicated in the development of atherosclerosis and certain autoimmune diseases, and is reported to induce tissue-type plasminogen activator (tPA) at the protein level in endothelial cells. This study was designed to investigate the effect of lysoPC on tPA gene expression and the underlying molecular mechanisms in cultured endothelial cells. LysoPC transiently induced the mRNA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15721275
DOI: 10.1016/j.bbrc.2005.01.094

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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