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Article

Regulation of tyrosine phosphorylation of PYK2 in vascular endothelial cells by lysophosphatidylcholine.

American journal of physiology. Heart and circulatory physiology - 1 Jul 2001

Rikitake Y, Kawashima S, Takahashi T, Ueyama T, Ishido S, Inoue N, Hirata K, Yokoyama M

Abstract excerpt

Lysophosphatidylcholine (LPC), a component of oxidized low-density lipoprotein, exerts various biological effects on vascular endothelial cells. However, the intracellular signaling of LPC is poorly understood. In this study, we investigated the involvement of proline-rich tyrosine kinase (PYK2) in LPC signaling in cultured bovine aortic endothelial cells by immunoprecipitation and Western blotting assays....

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Identifiers

PMID: 11406493
DOI: 10.1152/ajpheart.2001.281.1.H266

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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