Article
The effect of heparin on osteoblast differentiation and activity in primary cultures of bovine aortic smooth muscle cells.
Atherosclerosis - 1 Mar 2005
Yang Lufang, Butcher Martin, Simon Ryan R, Osip Stephanie L, Shaughnessy Stephen G
Abstract excerpt
Recent studies have suggested that aortic smooth muscle cells undergo a phenotypic transition into osteoblast-like cells and mineralize when cultured in the presence of beta-glycerophosphate. Since we had previously demonstrated that heparin could inhibit osteoblast differentiation and mineralization in primary cultures of murine calvaria cells, we were interested in determining if heparin would have a similar...
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