Article
Differential effects of 17beta-estradiol and raloxifene on VSMC phenotype and expression of osteoblast-associated proteins.
American journal of physiology. Endocrinology and metabolism - 1 Jul 2005
Rzewuska-Lech Ewa, Jayachandran Muthuvel, Fitzpatrick Lorraine A, Miller Virginia M
Abstract excerpt
Several studies demonstrate an association between osteoporosis and arterial calcific disease, both of which being common in elderly women. Estradiol and raloxifene, a selective estrogen receptor modulator, prevent bone loss in postmenopausal women. Little is known regarding how these agents affect arterial calcification. The aim of this study was to determine whether or not 17beta-estradiol and raloxifene...
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