Article
Host plasminogen activator inhibitor-1 promotes human skin carcinoma progression in a stage-dependent manner.
Neoplasia (New York, N.Y.) - 1 Jan 2005
Maillard Catherine, Jost Maud, Rømer Maria Unni, Brunner Nils, Houard Xavier, Lejeune Annabelle, Munaut Carine, Bajou Khalid, Melen Laurence, Dano Keld, Carmeliet Peter, Fusenig Norbert E, Foidart Jean Michel, Noel Agnès
Abstract excerpt
Angiogenesis and tumor expansion are associated with extracellular matrix remodeling and involve various proteases such as the plasminogen (Plg)/plasminogen activator (PA) system. Recently, several experimental data have implicated the plasminogen activator inhibitor-1 (PAI-1) in tumor angiogenes...
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