Article
Modulation of the angiogenesis response through Ha-ras control, placenta growth factor, and angiopoietin expression in mouse skin carcinogenesis.
Molecular carcinogenesis - 1 Jun 2003
Larcher Fernando, Franco Marcela, Bolontrade Marcela, Rodriguez-Puebla Marcelo, Casanova Llanos, Navarro Manuel, Yancopoulos George, Jorcano José L, Conti Claudio J
Abstract excerpt
Tumor angiogenesis is governed by a complex balance of positive and negative angiogenic factors. Development of chemically-induced mouse skin tumors appears to be highly dependent on an early burst of neovascularization. We have previously shown that Ha-ras-driven vascular endothelial growth fact...
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